PR002516 (Project)

Description:This project focuses on untargeted metabolomic analysis of human plasma samples using advanced mass spectrometry techniques (LC-MS). The goal is to (1) characterize the metabolic profile of human plasma; (2) identify potential biomarkers or metabolic pathways associated with sudden sensorineural hearing loss (SSNHL); (3) provide foundational metabolomic data for further biomedical research. Raw data, analytical methods, and metabolite annotations are submitted for transparency and reproducibility. In this study, non-targeted metabolomic analysis revealed that the differentially expressed metabolites in plasma of SSNHL patients mainly focus on lipid and lipid-like molecules, amino acids and their derivatives, flavonoids, as well as organic oxygen compounds involved in central carbon metabolism and energy metabolic pathways such as tricarboxylic acid cycle intermediates.