PR000625 (Project)

Dcc Asset:

MW submission packet 20260611.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Child Project:

PPR00001

Project (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8W983

Description:Non-invasive biomarkers are needed in inflammatory bowel disease (IBD) to help define disease activity and identify underlying pathogenic mechanisms. We hypothesized that serum metabolomics, which produces unique metabolite profiles, can aid in this search. The aim of this study was to characterize serum metabolomic profiles in patients with IBD, and to assess for differences between patients with ulcerative colitis (UC), Crohn disease (CD), and non-IBD subjects. Serum samples from 20 UC, 20 CD, and 20 non-IBD control subjects were obtained along with patient characteristics, including medication use and clinical disease activity. Non-targeted metabolomic profiling was performed using ultra-high performance liquid chromatography/mass spectrometry (UPLC-MS/MS) optimized for basic or acidic species and hydrophilic interaction liquid chromatography (HILIC/UPLC-MS/MS).

Results found

Linked to

	Label	Description
	SU000936 Subject (Entity type)	A subject produced as part of the PR000625 project
	SA052830 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052833 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052861 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052850 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052843 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052824 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052868 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052838 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project
	SA052853 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000625 project

SU000936

Subject (Entity type)

A subject produced as part of the PR000625 project

SA052830

Biosample (Entity type)