Osteoarthritis (Phenotype)

Synonyms:HP:0001379, HP:0002824, HP:0005762, Degenerative joint disease

Id:HP:0002758

Description:Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.

Results found

Linked to

	Label	Description
	GNAS Gene (Entity type)	ENSG00000087460 - GNAS complex locus
	FABP4 Gene (Entity type)	ENSG00000170323 - fatty acid binding protein 4
	HPGD Gene (Entity type)	ENSG00000164120 - 15-hydroxyprostaglandin dehydrogenase
	FGFR3 Gene (Entity type)	ENSG00000068078 - fibroblast growth factor receptor 3
	FABP5 Gene (Entity type)	ENSG00000164687 - fatty acid binding protein 5
	ASPN Gene (Entity type)	ENSG00000106819 - asporin
	LGALS1 Gene (Entity type)	ENSG00000100097 - galectin 1
	SLC26A2 Gene (Entity type)	ENSG00000155850 - solute carrier family 26 member 2
	COMP Gene (Entity type)	ENSG00000105664 - cartilage oligomeric matrix protein
	CNN3 Gene (Entity type)	ENSG00000117519 - calponin 3

GNAS

Gene (Entity type)

ENSG00000087460 - GNAS complex locus

FABP4

Gene (Entity type)

ENSG00000170323 - fatty acid binding protein 4

HPGD

Gene (Entity type)

ENSG00000164120 - 15-hydroxyprostaglandin dehydrogenase

FGFR3

Gene (Entity type)

ENSG00000068078 - fibroblast growth factor receptor 3

FABP5

Gene (Entity type)

ENSG00000164687 - fatty acid binding protein 5

ASPN

Gene (Entity type)

ENSG00000106819 - asporin

LGALS1

Gene (Entity type)

ENSG00000100097 - galectin 1

SLC26A2

Gene (Entity type)

ENSG00000155850 - solute carrier family 26 member 2

COMP

Gene (Entity type)

ENSG00000105664 - cartilage oligomeric matrix protein

CNN3

Gene (Entity type)

ENSG00000117519 - calponin 3

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.