LDHA (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:3939, GSD11, HEL-S-133P, HGNC:6535, LDHA, LDHM, MIM:150000, NM_001135239, NM_001165414, NM_001165415, NM_001165416, NM_005566, NP_001128711, NP_001158886, NP_001158887, NP_001158888, NP_005557, NR_028500, PIG19, lactate dehydrogenase A

Id:ENSG00000288299

Description:lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]

This gene encodes the A subunit of lactate dehydrogenase enzyme which catalyzes the reversible conversion of pyruvate to lactate with the concomitant oxidation of NADH to NAD in anaerobic glycolysis. The protein is found predominantly in skeletal muscle and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2023]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LDHA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LDHA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LDHA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LDHA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LDHA.

Results found

Linked to

	Label	Description
	Acute kidney injury Phenotype (Entity type)	Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum crea...
	Chronic kidney disease Phenotype (Entity type)	Functional anomaly of the kidney persisting for at least three months.
	Cachexia Phenotype (Entity type)	Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic d...

Acute kidney injury

Phenotype (Entity type)

Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum crea...

Chronic kidney disease

Phenotype (Entity type)

Functional anomaly of the kidney persisting for at least three months.

Cachexia

Phenotype (Entity type)

Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic d...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.