NDUFS3 (Gene)

Organism:

Homo sapiens

Synonyms:CI-30, ENTREZ:4722, HGNC:7710, MC1DN8, MIM:603846, NADH:ubiquinone oxidoreductase core subunit S3, NDUFS3, NM_004551, NP_004542

Id:ENSG00000285387

Description:NADH:ubiquinone oxidoreductase core subunit S3 [Source:HGNC Symbol;Acc:HGNC:7710]

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NDUFS3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NDUFS3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NDUFS3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NDUFS3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NDUFS3.

Results found

Linked to

	Label	Description
	Hypoglycemia Phenotype (Entity type)	A decreased concentration of glucose in the blood.
	Pancreatitis Phenotype (Entity type)	The presence of inflammation in the pancreas.
	Abnormality of mitochondrial metabolism Phenotype (Entity type)	A functional anomaly of mitochondria.

Hypoglycemia

Phenotype (Entity type)

A decreased concentration of glucose in the blood.

Pancreatitis

Phenotype (Entity type)

The presence of inflammation in the pancreas.

Abnormality of mitochondrial metabolism

Phenotype (Entity type)

A functional anomaly of mitochondria.

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.