GCNT2 (Gene)

Organism:

Homo sapiens

Synonyms:CCAT, CTRCT13, ENTREZ:2651, GCNT2, GCNT2C, GCNT5, HGNC:4204, IGNT, II, MIM:600429, NACGT1, NAGCT1, NM_001374747, NM_001491, NM_145649, NM_145655, NP_001361676, NP_001482, NP_663624, NP_663630, ULG3, XM_005248997, XM_005248999, XM_006715052, XM_011514468, XM_017010732, XP_005249054, XP_005249056, XP_006715115, XP_011512770, XP_016866221, XR_002956275, XR_926136, bA360O19.2, bA421M1.1, glucosaminyl (N-acetyl) transferase 2 (I blood group)

Id:ENSG00000285222

Description:glucosaminyl (N-acetyl) transferase 2 (I blood group) [Source:HGNC Symbol;Acc:HGNC:4204]

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GCNT2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GCNT2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GCNT2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GCNT2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GCNT2.

Results found

Linked to

	Label	Description
	Hypospadias Phenotype (Entity type)	Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...
	Obesity Phenotype (Entity type)	Accumulation of substantial excess body fat.
	Anxiety Phenotype (Entity type)	Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...
	Depression Phenotype (Entity type)	Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...
	Autism Phenotype (Entity type)	Autism is a neurodevelopmental disorder characterized by impaired social interaction and communicati...
	Stroke Phenotype (Entity type)	Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to t...
	Cachexia Phenotype (Entity type)	Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic d...
	Bipolar affective disorder Phenotype (Entity type)	Bipolar disorder is an illness of mood characterized by alternating episodes of elevated and depress...

Hypospadias

Phenotype (Entity type)

Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...

Obesity

Phenotype (Entity type)

Accumulation of substantial excess body fat.

Anxiety

Phenotype (Entity type)

Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...

Depression

Phenotype (Entity type)

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...

Autism

Phenotype (Entity type)

Autism is a neurodevelopmental disorder characterized by impaired social interaction and communicati...

Stroke

Phenotype (Entity type)

Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to t...

Cachexia

Phenotype (Entity type)

Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic d...

Bipolar affective disorder

Phenotype (Entity type)

Bipolar disorder is an illness of mood characterized by alternating episodes of elevated and depress...

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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