NFKBIB (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:4793, HGNC:7798, IKBB, MIM:604495, NFKB inhibitor beta, NFKBIB, NM_001001716, NM_001243116, NM_001369699, NM_001369700, NM_002503, NP_001230045, NP_001356628, NP_001356629, NP_002494, NR_040515, NR_161470, TRIP9, XM_006723226, XM_006723227, XP_006723289, XP_006723290

Id:ENSG00000282905

Description:NFKB inhibitor beta [Source:HGNC Symbol;Acc:HGNC:7798]

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NFKBIB's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NFKBIB.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NFKBIB.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NFKBIB.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NFKBIB.

Results found

Linked to

	Label	Description
	Hypospadias Phenotype (Entity type)	Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...
	Obesity Phenotype (Entity type)	Accumulation of substantial excess body fat.
	Myopathy Phenotype (Entity type)	A disorder of muscle unrelated to impairment of innervation or neuromuscular junction.
	Autism Phenotype (Entity type)	Autism is a neurodevelopmental disorder characterized by impaired social interaction and communicati...

Hypospadias

Phenotype (Entity type)

Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...

Obesity

Phenotype (Entity type)

Accumulation of substantial excess body fat.

Myopathy

Phenotype (Entity type)

A disorder of muscle unrelated to impairment of innervation or neuromuscular junction.

Autism

Phenotype (Entity type)

Autism is a neurodevelopmental disorder characterized by impaired social interaction and communicati...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.