SLC37A4 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:2542, G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, HGNC:4061, MIM:602671, NM_001164277, NM_001164278, NM_001164279, NM_001164280, NM_001467, NP_001157749, NP_001157750, NP_001157751, NP_001157752, NP_001458, PRO0685, SLC37A4, TRG-19, TRG19, solute carrier family 37 member 4

Id:ENSG00000281500

Description:solute carrier family 37 member 4 [Source:HGNC Symbol;Acc:HGNC:4061]

This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.[provided by RefSeq, Aug 2009]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SLC37A4's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SLC37A4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SLC37A4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SLC37A4.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SLC37A4.

Results found

Linked to

	Label	Description
	Hypertension Phenotype (Entity type)	The presence of chronic increased pressure in the systemic arterial system.
	Osteoporosis Phenotype (Entity type)	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...
	Hypoglycemia Phenotype (Entity type)	A decreased concentration of glucose in the blood.
	Arthritis Phenotype (Entity type)	Inflammation of a joint.
	Carious teeth Phenotype (Entity type)	Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...
	Chronic kidney disease Phenotype (Entity type)	Functional anomaly of the kidney persisting for at least three months.
	Hyperlipidemia Phenotype (Entity type)	An elevated lipid concentration in the blood.
	Pancreatitis Phenotype (Entity type)	The presence of inflammation in the pancreas.
	Colitis Phenotype (Entity type)	Colitis refers to an inflammation of the colon and is often used to describe an inflammation of the ...
	Periodontitis Phenotype (Entity type)	Inflammation of the periodontium.

Hypertension

Phenotype (Entity type)

The presence of chronic increased pressure in the systemic arterial system.

Osteoporosis

Phenotype (Entity type)

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...

Hypoglycemia

Phenotype (Entity type)

A decreased concentration of glucose in the blood.

Arthritis

Phenotype (Entity type)

Inflammation of a joint.

Carious teeth

Phenotype (Entity type)

Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...

Chronic kidney disease

Phenotype (Entity type)

Functional anomaly of the kidney persisting for at least three months.

Hyperlipidemia

Phenotype (Entity type)

An elevated lipid concentration in the blood.

Pancreatitis

Phenotype (Entity type)

The presence of inflammation in the pancreas.

Colitis

Phenotype (Entity type)

Colitis refers to an inflammation of the colon and is often used to describe an inflammation of the ...

Periodontitis

Phenotype (Entity type)

Inflammation of the periodontium.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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