NR2E3 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:10002, ESCS, HGNC:7974, MIM:604485, NM_001281446, NM_014249, NM_016346, NP_055064, NP_057430, NR2E3, PNR, RNR, RP37, nuclear receptor subfamily 2 group E member 3, rd7

Omim:OMIM:604485

Id:cd29aa67-71b1-54b2-b22e-3bc54fa78a98

Hgnc:HGNC:7974

Entrez:10002

Ensembl:ENSG00000278570

Description:nuclear receptor subfamily 2 group E member 3

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NR2E3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NR2E3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NR2E3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NR2E3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NR2E3.

Results found

Linked to

	Label	Description
	GSE164874 5 V 10 PREDNISOLONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE226285 3 V 1 GLUTATHIONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE164874 prednisolone muscle organ 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE198930 prunetin AGS 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	Obesity Phenotype (Entity type)	Accumulation of substantial excess body fat.
	GSE192870 2 V 0 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE164874 5 V 1 PREDNISOLONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	Glaucoma Phenotype (Entity type)	Glaucoma refers loss of retinal ganglion cells in a characteristic pattern of optic neuropathy usual...
	GSE164874 prednisolone muscle organ 5 v 13 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE164874 5 V 10 PREDNISOLONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE226285 3 V 1 GLUTATHIONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE164874 prednisolone muscle organ 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE198930 prunetin AGS 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Obesity

Phenotype (Entity type)

Accumulation of substantial excess body fat.

GSE192870 2 V 0 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE164874 5 V 1 PREDNISOLONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Glaucoma

Phenotype (Entity type)

Glaucoma refers loss of retinal ganglion cells in a characteristic pattern of optic neuropathy usual...

GSE164874 prednisolone muscle organ 5 v 13 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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