LILRB5 (Gene)

Organism:

Homo sapiens

Synonyms:CD85C, ENTREZ:10990, HGNC:6609, LILRB5, LIR-8, LIR8, MIM:604814, NM_001081442, NM_001081443, NM_001304457, NM_006840, NP_001074911, NP_001074912, NP_001291386, NP_006831, XM_011526359, XM_011526360, XM_011526361, XM_011526362, XP_011524661, XP_011524662, XP_011524663, XP_011524664, XR_935722, XR_935723, leukocyte immunoglobulin like receptor B5

Id:ENSG00000278437

Description:leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609]

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LILRB5's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LILRB5.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LILRB5.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LILRB5.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LILRB5.

Results found

Linked to

	Label	Description
	Systemic lupus erythematosus Phenotype (Entity type)	A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, c...
	Hyperlipidemia Phenotype (Entity type)	An elevated lipid concentration in the blood.
	Cholelithiasis Phenotype (Entity type)	Hard, pebble-like deposits that form within the gallbladder.
	Autoimmunity Phenotype (Entity type)	The occurrence of an immune reaction against the organism's own cells or tissues.
	Depression Phenotype (Entity type)	Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...
	Osteoporosis Phenotype (Entity type)	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...
	Hepatic failure Phenotype (Entity type)	A Phenotype
	Arthralgia Phenotype (Entity type)	Joint pain.
	Bipolar affective disorder Phenotype (Entity type)	Bipolar disorder is an illness of mood characterized by alternating episodes of elevated and depress...
	Atherosclerosis Phenotype (Entity type)	A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls ...

Systemic lupus erythematosus

Phenotype (Entity type)

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, c...

Hyperlipidemia

Phenotype (Entity type)

An elevated lipid concentration in the blood.

Cholelithiasis

Phenotype (Entity type)

Hard, pebble-like deposits that form within the gallbladder.

Autoimmunity

Phenotype (Entity type)

The occurrence of an immune reaction against the organism's own cells or tissues.

Depression

Phenotype (Entity type)

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...

Osteoporosis

Phenotype (Entity type)

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...

Hepatic failure

Phenotype (Entity type)

A Phenotype

Arthralgia

Phenotype (Entity type)

Joint pain.

Bipolar affective disorder

Phenotype (Entity type)

Bipolar disorder is an illness of mood characterized by alternating episodes of elevated and depress...

Atherosclerosis

Phenotype (Entity type)

A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls ...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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