CARS1 (Gene)

Organism:

Homo sapiens

Synonyms:CARS, CARS1, CYSRS, ENTREZ:833, HGNC:1493, MCDDBH, MDBH, MGC:11246, MIM:123859, NM_001014437, NM_001014438, NM_001194997, NM_001378136, NM_001378137, NM_001378138, NM_001378139, NM_001378140, NM_001751, NM_139273, NP_001014437, NP_001181926, NP_001365065, NP_001365066, NP_001365067, NP_001365068, NP_001365069, NP_001742, NP_644802, NR_036542, NR_165428, NR_165429, NR_165430, XM_024448701, XM_024448702, XM_024448703, XM_024448704, XM_024448705, XP_024304469, XP_024304470, XP_024304471, XP_024304472, XP_024304473, XR_001747998, XR_002957203, XR_002957204, XR_930913, XR_930914, cysteinyl-tRNA synthetase 1

Id:ENSG00000278191

Description:cysteinyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:1493]

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CARS1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CARS1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CARS1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CARS1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CARS1.

Results found

Linked to

	Label	Description
	Hypospadias Phenotype (Entity type)	Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...
	Hypertension Phenotype (Entity type)	The presence of chronic increased pressure in the systemic arterial system.
	Depression Phenotype (Entity type)	Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...
	Autoimmunity Phenotype (Entity type)	The occurrence of an immune reaction against the organism's own cells or tissues.
	Alopecia Phenotype (Entity type)	A noncongenital process of hair loss, which may progress to partial or complete baldness.
	Small for gestational age Phenotype (Entity type)	Smaller than normal size according to sex and gestational age related norms, defined as a weight bel...
	Arthralgia Phenotype (Entity type)	Joint pain.
	Arthritis Phenotype (Entity type)	Inflammation of a joint.
	Eczematoid dermatitis Phenotype (Entity type)	Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...
	Carious teeth Phenotype (Entity type)	Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...

Hypospadias

Phenotype (Entity type)

Abnormal position of urethral meatus on the ventral penile shaft (underside) characterized by displa...

Hypertension

Phenotype (Entity type)

The presence of chronic increased pressure in the systemic arterial system.

Depression

Phenotype (Entity type)

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...

Autoimmunity

Phenotype (Entity type)

The occurrence of an immune reaction against the organism's own cells or tissues.

Alopecia

Phenotype (Entity type)

A noncongenital process of hair loss, which may progress to partial or complete baldness.

Small for gestational age

Phenotype (Entity type)

Smaller than normal size according to sex and gestational age related norms, defined as a weight bel...

Arthralgia

Phenotype (Entity type)

Joint pain.

Arthritis

Phenotype (Entity type)

Inflammation of a joint.

Eczematoid dermatitis

Phenotype (Entity type)

Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

Carious teeth

Phenotype (Entity type)

Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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