CCL18 (Gene)

Organism:

Homo sapiens

Synonyms:AMAC-1, AMAC1, C-C motif chemokine ligand 18, CCL18, CKb7, DC-CK1, DCCK1, ENTREZ:6362, HGNC:10616, MIM:603757, MIP-4, NM_002988, NP_002979, PARC, SCYA18

Id:ENSG00000278167

Description:C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616]

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CCL18's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CCL18.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CCL18.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CCL18.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CCL18.

Results found

Linked to

	Label	Description
	Eczematoid dermatitis Phenotype (Entity type)	Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

Eczematoid dermatitis

Phenotype (Entity type)

Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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