PRODH (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:102724788, LOC102724788, NM_001368249, NM_001368250, NP_001355178, NP_001355179, XM_006724936, XM_017030167, XM_017030169, XM_017030170, XM_024452505, XP_006724999, XP_016885656, XP_016885658, XP_016885659, XP_024308273, XR_951398, proline dehydrogenase 1, mitochondrial

Id:ENSG00000277196

Description:proline dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:9453]

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRODH's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PRODH.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRODH.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRODH.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRODH.

Results found

Linked to

	Label	Description
	MDA-MB-468-ploc-paclitaxel Biosample (Entity type)	A biosample from Bridge2AI produced as part of the cm4ai project
	MDA-MB-468-ploc-vorinostat Biosample (Entity type)	A biosample from Bridge2AI produced as part of the cm4ai project
	Nephropathy Phenotype (Entity type)	A nonspecific term referring to disease or damage of the kidneys.
	Schizophrenia Phenotype (Entity type)	A mental disorder characterized by a disintegration of thought processes and emotional responsivenes...

MDA-MB-468-ploc-paclitaxel

Biosample (Entity type)

A biosample from Bridge2AI produced as part of the cm4ai project

MDA-MB-468-ploc-vorinostat

Biosample (Entity type)

A biosample from Bridge2AI produced as part of the cm4ai project

Nephropathy

Phenotype (Entity type)

A nonspecific term referring to disease or damage of the kidneys.

Schizophrenia

Phenotype (Entity type)

A mental disorder characterized by a disintegration of thought processes and emotional responsivenes...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.