MIF (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:4282, GIF, GLIF, HGNC:7097, MIF, MIM:153620, MMIF, NM_002415, NP_002406, macrophage migration inhibitory factor

Id:ENSG00000276701

Description:macrophage migration inhibitory factor [Source:HGNC Symbol;Acc:HGNC:7097]

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MIF's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MIF.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MIF.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MIF.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MIF.

Results found

Linked to

	Label	Description
	Anxiety Phenotype (Entity type)	Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...
	Autoimmunity Phenotype (Entity type)	The occurrence of an immune reaction against the organism's own cells or tissues.
	Depression Phenotype (Entity type)	Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...
	Osteoporosis Phenotype (Entity type)	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...
	Arthritis Phenotype (Entity type)	Inflammation of a joint.
	Arthralgia Phenotype (Entity type)	Joint pain.
	Rheumatoid arthritis Phenotype (Entity type)	Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid de...
	Asthma Phenotype (Entity type)	Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli...

Anxiety

Phenotype (Entity type)

Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...

Autoimmunity

Phenotype (Entity type)

The occurrence of an immune reaction against the organism's own cells or tissues.

Depression

Phenotype (Entity type)

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...

Osteoporosis

Phenotype (Entity type)

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...

Arthritis

Phenotype (Entity type)

Inflammation of a joint.

Arthralgia

Phenotype (Entity type)

Joint pain.

Rheumatoid arthritis

Phenotype (Entity type)

Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid de...

Asthma

Phenotype (Entity type)

Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.