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H4C9 (Gene)

Entrez:8294
Ensembl:ENSG00000276180
Description:H4 clustered histone 9
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View H4C9's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with H4C9.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using H4C9.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for H4C9.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with H4C9.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE212330 azacitidine 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE169617 azacitidine 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE172016 paclitaxel 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE182150 KIT LSD1 MYC inhibition 6 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193351 ruxolitinib 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876 GSE147877 enzalutamide MR42D 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE60217 adenosine 1 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE182680 GSE182683 dexamethasone 5 v 12 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE229663 GSE229666 menin inhibition 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE173201 cisplatin 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE212330 azacitidine 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE169617 azacitidine 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE172016 paclitaxel 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE182150 KIT LSD1 MYC inhibition 6 v 8 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193351 ruxolitinib 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876 GSE147877 enzalutamide MR42D 4 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE60217 adenosine 1 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE182680 GSE182683 dexamethasone 5 v 12 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE229663 GSE229666 menin inhibition 3 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE173201 cisplatin 2 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.