CCL16 (Gene)

Omim:OMIM:601394

Id:be7010a6-777c-5e8b-946c-ad3547a0d80e

Hgnc:HGNC:10614

Entrez:6360

Description:C-C motif chemokine ligand 16

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CCL16's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CCL16.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CCL16.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CCL16.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CCL16.

Results found

Linked to

	Label	Description
	GSE195663 cisplatin 7 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE56010 adenosine 4 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE109140 2 V 3 VALPROIC ACID HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE193838 catechin 0 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE195663 7 V 1 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 8 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193838 catechin 0 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE192771 2 V 0 SORAFENIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE261563 CX-5461 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE168604 GSE183859 selumetinib 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE195663 cisplatin 7 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE56010 adenosine 4 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE109140 2 V 3 VALPROIC ACID HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE193838 catechin 0 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE195663 7 V 1 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 8 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193838 catechin 0 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE192771 2 V 0 SORAFENIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE261563 CX-5461 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE168604 GSE183859 selumetinib 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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