DGKK (Gene)

Organism:

Homo sapiens

Synonyms:DGKK, ENTREZ:139189, HGNC:32395, MIM:300837, NM_001013742, NP_001013764, XM_017029268, XP_016884757, diacylglycerol kinase kappa

Omim:OMIM:300837

Id:ENSG00000274588

Hgnc:HGNC:32395

Entrez:139189

Ensembl:ENSG00000274588

Description:diacylglycerol kinase kappa

The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DGKK's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DGKK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DGKK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DGKK.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DGKK.

Results found

Linked to

	Label	Description
	GSE218773 ABL2 knockdown Hep-G2 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE187006 3 V 2 VALPROIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE100148 EZH2 inhibition 10 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE189653,GSE203344 5 V 3 FLUOXETINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158552 BRD4 inhibition 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE154074 5 V 0 BLEOMYCIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE142210 4 V 7 PANOBINOSTAT HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 11 V 6 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 0 V 12 LENALIDOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE218773 ABL2 knockdown Hep-G2 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE187006 3 V 2 VALPROIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE100148 EZH2 inhibition 10 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE189653,GSE203344 5 V 3 FLUOXETINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158552 BRD4 inhibition 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE154074 5 V 0 BLEOMYCIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE142210 4 V 7 PANOBINOSTAT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE216043 11 V 6 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 0 V 12 LENALIDOMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.