Synonyms:ARHGAP23, ENTREZ:57636, HGNC:29293, MIM:610590, NM_001199417, NM_020876, NP_001186346, Rho GTPase activating protein 23, XM_006721991, XM_006721992, XM_006721993, XM_011525073, XM_011525074, XM_011525075, XM_011525076, XM_011525077, XM_017024902, XM_024450847, XP_006722054, XP_006722055, XP_006722056, XP_011523375, XP_011523376, XP_011523377, XP_011523378, XP_011523379, XP_016880391, XP_024306615, XR_429909
Id:ENSG00000273780
Description:Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293]
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
