CTSO (Gene)

Organism:

Homo sapiens

Synonyms:CTSO, CTSO1, ENTREZ:1519, HGNC:2542, MIM:600550, NM_001334, NP_001325, cathepsin O

Id:ENSG00000263238

Description:cathepsin O [Source:HGNC Symbol;Acc:HGNC:2542]

The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CTSO's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CTSO.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CTSO.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CTSO.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CTSO.

Results found

Linked to

	Label	Description
	Hypertension Phenotype (Entity type)	The presence of chronic increased pressure in the systemic arterial system.
	Osteoporosis Phenotype (Entity type)	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...
	Hypoglycemia Phenotype (Entity type)	A decreased concentration of glucose in the blood.
	Arthritis Phenotype (Entity type)	Inflammation of a joint.
	Carious teeth Phenotype (Entity type)	Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...
	Chronic kidney disease Phenotype (Entity type)	Functional anomaly of the kidney persisting for at least three months.
	Hyperlipidemia Phenotype (Entity type)	An elevated lipid concentration in the blood.
	Pancreatitis Phenotype (Entity type)	The presence of inflammation in the pancreas.
	Colitis Phenotype (Entity type)	Colitis refers to an inflammation of the colon and is often used to describe an inflammation of the ...
	Periodontitis Phenotype (Entity type)	Inflammation of the periodontium.

Hypertension

Phenotype (Entity type)

The presence of chronic increased pressure in the systemic arterial system.

Osteoporosis

Phenotype (Entity type)

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...

Hypoglycemia

Phenotype (Entity type)

A decreased concentration of glucose in the blood.

Arthritis

Phenotype (Entity type)

Inflammation of a joint.

Carious teeth

Phenotype (Entity type)

Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has b...

Chronic kidney disease

Phenotype (Entity type)

Functional anomaly of the kidney persisting for at least three months.

Hyperlipidemia

Phenotype (Entity type)

An elevated lipid concentration in the blood.

Pancreatitis

Phenotype (Entity type)

The presence of inflammation in the pancreas.

Colitis

Phenotype (Entity type)

Colitis refers to an inflammation of the colon and is often used to describe an inflammation of the ...

Periodontitis

Phenotype (Entity type)

Inflammation of the periodontium.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.