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HLA-DQA2 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CELIAC1, DC-alpha, DQ-A1, DQA1, DX-ALPHA, ENTREZ:3117, ENTREZ:3118, HGNC:4942, HGNC:4943, HLA-DCA, HLA-DQA, HLA-DQA1, HLA-DQA2, HLA-DXA, HLADQA2, MIM:146880, MIM:613503, NM_002122, NM_020056, NP_002113, NP_064440, XM_006715079, XP_006715142, major histocompatibility complex, class II, DQ alpha 1, major histocompatibility complex, class II, DQ alpha 2
Omim:OMIM:613503
Id:ENSG00000237541
Hgnc:HGNC:4943
Entrez:3118
Ensembl:ENSG00000237541
Description:major histocompatibility complex, class II, DQ alpha 2
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DQA2's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-DQA2.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DQA2.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DQA2.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DQA2.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE216540 fulvestrant 10 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216540 1 V 6 FULVESTRANT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216540 10 V 6 FULVESTRANT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216540 fulvestrant 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE130437 palbociclib 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE238018 MXRA8 knockout MDA-MB-231 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE130437 2 V 1 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216540 0 V 6 FULVESTRANT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE152642 GSE153671 KMT2D inhibition 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE208781 GSE208784 dopamine 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE216540 fulvestrant 10 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216540 1 V 6 FULVESTRANT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216540 10 V 6 FULVESTRANT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216540 fulvestrant 0 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE130437 palbociclib 2 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE238018 MXRA8 knockout MDA-MB-231 3 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE130437 2 V 1 PALBOCICLIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216540 0 V 6 FULVESTRANT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE152642 GSE153671 KMT2D inhibition 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE208781 GSE208784 dopamine 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.