CDSN (Gene)

Organism:

Homo sapiens

Synonyms:CDSN, ENTREZ:1041, HGNC:1802, HTSS, HTSS1, HYPT2, MIM:602593, NM_001264, NP_001255, PSS, PSS1, S, corneodesmosin

Id:ENSG00000237165

Description:corneodesmosin [Source:HGNC Symbol;Acc:HGNC:1802]

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. [provided by RefSeq, Dec 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CDSN's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CDSN.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CDSN.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CDSN.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CDSN.

Results found

Linked to

	Label	Description
	Alopecia Phenotype (Entity type)	A noncongenital process of hair loss, which may progress to partial or complete baldness.
	Allergy Phenotype (Entity type)	An allergy is an immune response or reaction to substances that are usually not harmful.
	Atopic dermatitis Phenotype (Entity type)	Atopic dermatitis (AD) or atopic eczema is an itchy, inflammatory skin condition with a predilection...
	Eczematoid dermatitis Phenotype (Entity type)	Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...
	Asthma Phenotype (Entity type)	Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli...

Alopecia

Phenotype (Entity type)

A noncongenital process of hair loss, which may progress to partial or complete baldness.

Allergy

Phenotype (Entity type)

An allergy is an immune response or reaction to substances that are usually not harmful.

Atopic dermatitis

Phenotype (Entity type)

Atopic dermatitis (AD) or atopic eczema is an itchy, inflammatory skin condition with a predilection...

Eczematoid dermatitis

Phenotype (Entity type)

Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

Asthma

Phenotype (Entity type)

Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli...

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.