HLA-DQA2 (Gene)

Organism:

Homo sapiens

Synonyms:CELIAC1, DC-alpha, DQ-A1, DQA1, DX-ALPHA, ENTREZ:3117, ENTREZ:3118, HGNC:4942, HGNC:4943, HLA-DCA, HLA-DQA, HLA-DQA1, HLA-DQA2, HLA-DXA, HLADQA2, MIM:146880, MIM:613503, NM_002122, NM_020056, NP_002113, NP_064440, XM_006715079, XP_006715142, major histocompatibility complex, class II, DQ alpha 1, major histocompatibility complex, class II, DQ alpha 2

Id:ENSG00000223793

Description:major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943]

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DQA2's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-DQA2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DQA2.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DQA2.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DQA2.

Results found

Linked to

	Label	Description
	Alopecia Phenotype (Entity type)	A noncongenital process of hair loss, which may progress to partial or complete baldness.
	Infertility Phenotype (Entity type)	A Phenotype
	Malnutrition Phenotype (Entity type)	A deficiency in the intake of energy and nutrients.
	Anxiety Phenotype (Entity type)	Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...
	Depression Phenotype (Entity type)	Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...
	Osteoporosis Phenotype (Entity type)	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...
	Arthralgia Phenotype (Entity type)	Joint pain.
	Eczematoid dermatitis Phenotype (Entity type)	Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

Alopecia

Phenotype (Entity type)

A noncongenital process of hair loss, which may progress to partial or complete baldness.

Infertility

Phenotype (Entity type)

A Phenotype

Malnutrition

Phenotype (Entity type)

A deficiency in the intake of energy and nutrients.

Anxiety

Phenotype (Entity type)

Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses...

Depression

Phenotype (Entity type)

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover fr...

Osteoporosis

Phenotype (Entity type)

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural...

Arthralgia

Phenotype (Entity type)

Joint pain.

Eczematoid dermatitis

Phenotype (Entity type)

Eczema is a form of dermatitis that is characterized by scaly, pruritic, erythematous lesions locate...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.