TAT (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Synonyms:ENTREZ:6898, HGNC:11573, MIM:613018, NM_000353, NP_000344, TAT, tyrosine aminotransferase

Omim:OMIM:613018

Id:ENSG00000198650

Hgnc:HGNC:11573

Entrez:6898

Ensembl:ENSG00000198650

Description:tyrosine aminotransferase

This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TAT's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TAT.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TAT.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TAT.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TAT.

Results found

Linked to

	Label	Description
	GSE108464 AZ-628 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE158552 BRD4 inhibition 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE185200 GSE185202 L-13 Ali-BL 0 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	Preweaning Lethality, Incomplete Penetrance (MP:0011110) Gene Set (Entity type)	A Gene Set from KOMP2
	GSE208350 H-7 Huh-7 JHH-7 4 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193838 catechin 0 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE169155 3 V 0 ACETAMINOPHEN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE184210 0 V 2 GLUCAGON MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE213845 EZH2 inhibition 3 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE108464 AZ-628 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE158552 BRD4 inhibition 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE185200 GSE185202 L-13 Ali-BL 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Preweaning Lethality, Incomplete Penetrance (MP:0011110)

Gene Set (Entity type)

A Gene Set from KOMP2

GSE208350 H-7 Huh-7 JHH-7 4 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193838 catechin 0 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE169155 3 V 0 ACETAMINOPHEN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE184210 0 V 2 GLUCAGON MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE213845 EZH2 inhibition 3 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.