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ADH1A (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ADH1, ADH1A, ENTREZ:124, HGNC:249, MIM:103700, NM_000667, NP_000658, alcohol dehydrogenase 1A (class I), alpha polypeptide
Omim:OMIM:103700
Id:562bdec6-6eb5-5d3c-8967-7c3420fbefde
Hgnc:HGNC:249
Entrez:124
Ensembl:ENSG00000187758
Description:alcohol dehydrogenase 1A (class I), alpha polypeptide
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ADH1A's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ADH1A.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ADH1A.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ADH1A.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ADH1A.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE226249 pirfenidone HL 0 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE226249 0 V 7 PIRFENIDONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE135030 11 V 10 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE226249 pirfenidone HL 0 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE226249 0 V 8 PIRFENIDONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Phenotype

Myopathy

Phenotype (Entity type)

A disorder of muscle unrelated to impairment of innervation or neuromuscular junction.

Gene Set

GSE226249 pirfenidone HL 0 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE116133 GSE116136 H-7 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE135686 etomoxir macrophage 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE226249 pirfenidone HL 0 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226249 0 V 7 PIRFENIDONE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE135030 11 V 10 FLUDARABINE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226249 pirfenidone HL 0 v 8 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226249 0 V 8 PIRFENIDONE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Phenotype

    Myopathy

    Phenotype (Entity type)

    A disorder of muscle unrelated to impairment of innervation or neuromuscular junction.

  • Gene Set

    GSE226249 pirfenidone HL 0 v 6 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE116133 GSE116136 H-7 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE135686 etomoxir macrophage 2 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.