MYT1L (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:23040, HGNC:7623, MIM:613084, MRD39, MYT1L, NM_001303052, NM_001329844, NM_001329845, NM_001329846, NM_001329847, NM_001329848, NM_001329849, NM_001329851, NM_001329852, NM_015025, NP_001289981, NP_001316773, NP_001316774, NP_001316775, NP_001316776, NP_001316777, NP_001316778, NP_001316780, NP_001316781, NP_055840, NZF1, XM_011510318, XM_011510319, XM_011510320, XM_011510321, XM_011510322, XM_011510323, XM_011510324, XM_011510325, XM_011510326, XM_011510327, XM_011510328, XM_011510331, XM_011510332, XM_017003604, XM_017003605, XM_017003606, XM_017003607, XM_017003608, XM_017003611, XM_017003612, XM_017003615, XM_017003616, XM_017003618, XM_017003620, XM_017003621, XM_017003622, XP_011508620, XP_011508621, XP_011508622, XP_011508623, XP_011508624, XP_011508625, XP_011508626, XP_011508627, XP_011508628, XP_011508629, XP_011508630, XP_011508633, XP_011508634, XP_016859093, XP_016859094, XP_016859095, XP_016859096, XP_016859097, XP_016859100, XP_016859101, XP_016859104, XP_016859105, XP_016859107, XP_016859109, XP_016859110, XP_016859111, ZC2H2C2, ZC2HC4B, myT1-L, myelin transcription factor 1 like

Omim:OMIM:613084

Id:93f731a0-3c97-573c-ba69-069b7b1a9f2a

Hgnc:HGNC:7623

Entrez:23040

Ensembl:ENSG00000186487

Description:myelin transcription factor 1 like

This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MYT1L's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MYT1L.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MYT1L.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MYT1L.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MYT1L.

Results found

Linked to

	Label	Description
	GSE120612 etoposide leukocyte 6 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE110178 2 V 3 TRANYLCYPROMINE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 4 V 1 ETOPOSIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 7 V 3 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE113655 phenol 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE100148 EZH2 inhibition 10 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE212312 FBXW7 knockout Reh 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680 GSE182683 dexamethasone 7 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE119978,GSE180930 0 V 4 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE207514,GSE207515 2 V 3 ACETYLCYSTEINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE120612 etoposide leukocyte 6 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE110178 2 V 3 TRANYLCYPROMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 4 V 1 ETOPOSIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 7 V 3 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE113655 phenol 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE100148 EZH2 inhibition 10 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE212312 FBXW7 knockout Reh 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680 GSE182683 dexamethasone 7 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE119978,GSE180930 0 V 4 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE207514,GSE207515 2 V 3 ACETYLCYSTEINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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