CYP11B2 (Gene)

Organism:

Homo sapiens

Synonyms:ALDOS, CPN2, CYP11B, CYP11B2, CYP11BL, CYPXIB2, ENTREZ:1585, HGNC:2592, MIM:124080, NM_000498, NP_000489, P-450C18, P450C18, P450aldo, cytochrome P450 family 11 subfamily B member 2

Omim:OMIM:124080

Id:ENSG00000179142

Hgnc:HGNC:2592

Entrez:1585

Ensembl:ENSG00000179142

Description:cytochrome P450 family 11 subfamily B member 2

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYP11B2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CYP11B2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYP11B2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYP11B2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYP11B2.

Results found

Linked to

	Label	Description
	GSE220520 3 V 4 ETHANOL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE264621 1 V 6 SECRETIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE236437 2 V 3 ALDOSTERONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE225735 1 V 4 ALDOSTERONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE220520 3 V 8 ETHANOL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	STBD1 Up Gene Set (Entity type)	A Gene Set from LINCS
	CMAP-PRISM-TP7 Up Gene Set (Entity type)	A Gene Set from LINCS
	EXTL2 Down Gene Set (Entity type)	A Gene Set from LINCS
	KU-C104218 Up Gene Set (Entity type)	A Gene Set from LINCS
	EDA Up Gene Set (Entity type)	A Gene Set from LINCS

GSE220520 3 V 4 ETHANOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE264621 1 V 6 SECRETIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE236437 2 V 3 ALDOSTERONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE225735 1 V 4 ALDOSTERONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE220520 3 V 8 ETHANOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

STBD1 Up

Gene Set (Entity type)

A Gene Set from LINCS

CMAP-PRISM-TP7 Up

Gene Set (Entity type)

A Gene Set from LINCS

EXTL2 Down

Gene Set (Entity type)

A Gene Set from LINCS

KU-C104218 Up

Gene Set (Entity type)

A Gene Set from LINCS

EDA Up

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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