HMGB4 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:127540, HGNC:24954, HMGB4, MIM:617285, NM_001352984, NM_001379301, NM_145205, NP_001339913, NP_001366230, NP_660206, dJ1007G16.5, high mobility group box 4

Omim:OMIM:617285

Id:ENSG00000176256

Hgnc:HGNC:24954

Entrez:127540

Ensembl:ENSG00000176256

Description:high mobility group box 4

Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HMGB4's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HMGB4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HMGB4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HMGB4.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HMGB4.

Results found

Linked to

	Label	Description
	GSE218580 1 V 0 FENTANYL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE210655 3 V 0 CISPLATIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE210655 3 V 2 CISPLATIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE199107 tryptophan 0 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE218580 1 V 2 FENTANYL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	TSSK4 IDG kinase ARCHS4 coexpression Gene Set (Entity type)	A Gene Set from IDG
	GTEx AdiposeTissue 20-29 vs 40-49 Down Gene Set (Entity type)	A Gene Set from GTEx
	GTEx Blood 20-29 vs 50-59 Up Gene Set (Entity type)	A Gene Set from GTEx
	GTEx Pituitary 20-29 vs 60-69 Up Gene Set (Entity type)	A Gene Set from GTEx
	GTEx SmallIntestine 20-29 vs 40-49 Up Gene Set (Entity type)	A Gene Set from GTEx

GSE218580 1 V 0 FENTANYL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE210655 3 V 0 CISPLATIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE210655 3 V 2 CISPLATIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE199107 tryptophan 0 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE218580 1 V 2 FENTANYL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

TSSK4 IDG kinase ARCHS4 coexpression

Gene Set (Entity type)

A Gene Set from IDG

GTEx AdiposeTissue 20-29 vs 40-49 Down

Gene Set (Entity type)

A Gene Set from GTEx

GTEx Blood 20-29 vs 50-59 Up

Gene Set (Entity type)

A Gene Set from GTEx

GTEx Pituitary 20-29 vs 60-69 Up

Gene Set (Entity type)

A Gene Set from GTEx

GTEx SmallIntestine 20-29 vs 40-49 Up

Gene Set (Entity type)

A Gene Set from GTEx

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.