CIDEA (Gene)

Organism:

Homo sapiens

Synonyms:CIDE-A, CIDEA, ENTREZ:1149, HGNC:1976, MIM:604440, NM_001279, NM_001318383, NP_001270, NP_001305312, NR_134607, cell death inducing DFFA like effector a

Id:ENSG00000176194

Entrez:1149

Ensembl:ENSG00000176194

Description:cell death inducing DFFA like effector a

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CIDEA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CIDEA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CIDEA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CIDEA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CIDEA.

Results found

Linked to

	Label	Description
	GSE129389 0 V 4 TROPIFEXOR MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE255432 6 V 0 IMEGLIMIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE162276 2 V 3 ROSIGLITAZONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE158632 2 V 4 OXYQUINOLINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE120370 0 V 6 THROMBIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE157904 3 V 1 DOXORUBICIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 6 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE129389 0 V 7 TROPIFEXOR MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS

GSE129389 0 V 4 TROPIFEXOR MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE255432 6 V 0 IMEGLIMIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE162276 2 V 3 ROSIGLITAZONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE158632 2 V 4 OXYQUINOLINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE120370 0 V 6 THROMBIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE157904 3 V 1 DOXORUBICIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 6 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE129389 0 V 7 TROPIFEXOR MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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