Synonyms:BF1, BF2, ENTREZ:2290, FHKL3, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1, FOXG1A, FOXG1B, FOXG1C, HBF-1, HBF-2, HBF-3, HBF-G2, HBF2, HFK1, HFK2, HFK3, HGNC:3811, KHL2, MIM:164874, NM_005249, NP_005240, QIN, forkhead box G1
Omim:OMIM:164874
Id:d8e5813b-55c9-587f-857a-27afdbe15cb0
Hgnc:HGNC:3811
Description:forkhead box G1
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020]