PNLIP (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:5406, HGNC:9155, MIM:246600, NM_000936, NP_000927, PL, PNLIP, PNLIPD, PTL, pancreatic lipase

Id:ENSG00000175535

Entrez:5406

Description:pancreatic lipase

This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea. [provided by RefSeq, Jul 2016]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PNLIP's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PNLIP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PNLIP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PNLIP.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PNLIP.

Results found

Linked to

	Label	Description
	GSE131887 5 V 2 DOXYCYCLINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 ruxolitinib 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 1 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 1 V 2 RUXOLITINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE115395 enzalutamide LNCaP 2 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE139427 2 V 1 IBRUTINIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE115395 2 V 5 ENZALUTAMIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 1 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214931 temozolomide 2 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE131887 5 V 2 DOXYCYCLINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 ruxolitinib 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 1 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 1 V 2 RUXOLITINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE115395 enzalutamide LNCaP 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE139427 2 V 1 IBRUTINIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE115395 2 V 5 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 1 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214931 temozolomide 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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