SLC22A1 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:6580, HGNC:10963, HOCT1, MIM:602607, NM_003057, NM_153187, NP_003048, NP_694857, OCT1, SLC22A1, XM_005267102, XM_005267103, XM_005267104, XM_005267105, XM_006715552, XM_011536074, XP_005267159, XP_005267160, XP_005267161, XP_005267162, XP_006715615, XP_011534376, oct1_cds, solute carrier family 22 member 1

Omim:OMIM:602607

Id:ENSG00000175003

Hgnc:HGNC:10963

Entrez:6580

Ensembl:ENSG00000175003

Description:solute carrier family 22 member 1

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SLC22A1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SLC22A1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SLC22A1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SLC22A1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SLC22A1.

Results found

Linked to

	Label	Description
	GSE171177,GSE171181 1 V 0 E7107 HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE228106 3 V 2 PACLITAXEL HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE235066 4 V 0 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE159678 4 V 2 CHLOROQUINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE236502 paclitaxel 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE130437 palbociclib 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE98856 adenosine 6 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE236502 1 V 3 PACLITAXEL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE130437 2 V 1 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE171177,GSE171181 1 V 0 E7107 HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE228106 3 V 2 PACLITAXEL HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE235066 4 V 0 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE159678 4 V 2 CHLOROQUINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE236502 paclitaxel 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE130437 palbociclib 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE98856 adenosine 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE236502 1 V 3 PACLITAXEL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE130437 2 V 1 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.