Synonyms:ENTREZ:2286, FKBP prolyl isomerase 2, FKBP-13, FKBP13, FKBP2, HGNC:3718, MIM:186946, NM_001135208, NM_001370360, NM_001370362, NM_001370363, NM_001370365, NM_001370367, NM_004470, NM_057092, NP_001128680, NP_001357289, NP_001357291, NP_001357292, NP_001357294, NP_001357296, NP_004461, NP_476433, PPIase
Omim:OMIM:186946
Id:ENSG00000173486
Hgnc:HGNC:3718
Description:FKBP prolyl isomerase 2
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]