Synonyms:CSP2, DSCR1L1, ENTREZ:10231, HGNC:3041, MCIP2, MIM:604876, NM_001251973, NM_001251974, NM_005822, NP_001238902, NP_001238903, NP_005813, RCAN2, RCN2, XM_011514226, XM_024446301, XP_011512528, XP_024302069, ZAKI-4, ZAKI4, regulator of calcineurin 2
Omim:OMIM:604876
Id:c4d60a97-5676-5661-9fd9-d8f51e7dbf2a
Hgnc:HGNC:3041
Description:regulator of calcineurin 2
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]