AZU1 (Gene)

Organism:

Homo sapiens

Synonyms:AZAMP, AZU, AZU1, CAP37, ENTREZ:566, HBP, HGNC:913, HUMAZUR, MIM:162815, NAZC, NM_001700, NP_001691, azurocidin 1, hHBP

Omim:OMIM:162815

Id:ENSG00000172232

Hgnc:HGNC:913

Entrez:566

Ensembl:ENSG00000172232

Description:azurocidin 1

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AZU1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with AZU1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AZU1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AZU1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AZU1.

Results found

Linked to

	Label	Description
	GSE114492 GSE153671 KMT2D inhibition 6 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE197555 0 V 3 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE212330 azacitidine 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 6 V 5 ETOPOSIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE238018 MXRA8 knockout MDA-MB-231 3 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130437 0 V 1 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 0 V 12 LENALIDOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE103510 STAT5 inhibition 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE114492 GSE153671 KMT2D inhibition 6 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE197555 0 V 3 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE212330 azacitidine 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 6 V 5 ETOPOSIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE238018 MXRA8 knockout MDA-MB-231 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130437 0 V 1 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 0 V 12 LENALIDOMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE103510 STAT5 inhibition 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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