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OPRPN (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Gene:

TARGET ID 03905

Collection (Entity type)
Synonyms:BPLP, ENTREZ:58503, HGNC:17279, MIM:608936, NM_001302807, NM_021225, NP_001289736, NP_067048, NR_126503, OPRPN, PRL1, PROL1, opiorphin prepropeptide, opiorphin
Id:ENSG00000171199
Entrez:58503
Ensembl:ENSG00000171199
Description:opiorphin prepropeptide
This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View OPRPN's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with OPRPN.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using OPRPN.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for OPRPN.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with OPRPN.

Results found

Linked to

 

Label

Description

 

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GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human dn

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GSE155987 LMTK2 knockdown CFBE41o- 0 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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GSE79395 ADNP knockdown HCT 116 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE85880,GSE85881 4 V 1 TRETINOIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE145692 EZH2 knockout SK-OV-3 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

Cleviprex Up

Gene Set (Entity type)

A Gene Set from LINCS

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SUFU Down

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

ZNF646 Down

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

YL-55 Up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE120792 BRCA1 inhibition Interferons 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE155987 LMTK2 knockdown CFBE41o- 0 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE79395 ADNP knockdown HCT 116 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880,GSE85881 4 V 1 TRETINOIN HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE145692 EZH2 knockout SK-OV-3 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    Cleviprex Up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    SUFU Down

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    ZNF646 Down

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    YL-55 Up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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