DNASE1L2 (Gene)

Organism:

Homo sapiens

Synonyms:DNAS1L2, DNASE1L2, ENTREZ:1775, HGNC:2958, MIM:602622, NM_001301680, NM_001374, NP_001288609, NP_001365, deoxyribonuclease 1 like 2

Omim:OMIM:602622

Id:ENSG00000167968

Hgnc:HGNC:2958

Entrez:1775

Ensembl:ENSG00000167968

Description:deoxyribonuclease 1 like 2

Predicted to enable DNA binding activity and deoxyribonuclease I activity. Predicted to be involved in DNA catabolic process, endonucleolytic. Predicted to act upstream of or within corneocyte development and hair follicle development. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DNASE1L2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DNASE1L2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DNASE1L2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DNASE1L2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DNASE1L2.

Results found

Linked to

	Label	Description
	GSE108464 AZ-628 6 v 15 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE245968 FOXA1 inhibition Receptors Steroid Acetyltransferases 3 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE143782 calcitriol 3 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE143782 calcitriol 3 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE168401 harmine U2OS 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE157904 3 V 1 DOXORUBICIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	Preweaning Lethality, Incomplete Penetrance (MP:0011110) Gene Set (Entity type)	A Gene Set from KOMP2
	GSE179235 MEK NRAS inhibition 0 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 cisplatin 3 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE145311 0 V 3 GLUTATHIONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

GSE108464 AZ-628 6 v 15 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE245968 FOXA1 inhibition Receptors Steroid Acetyltransferases 3 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE143782 calcitriol 3 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE143782 calcitriol 3 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE168401 harmine U2OS 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE157904 3 V 1 DOXORUBICIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Preweaning Lethality, Incomplete Penetrance (MP:0011110)

Gene Set (Entity type)

A Gene Set from KOMP2

GSE179235 MEK NRAS inhibition 0 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE216043 cisplatin 3 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE145311 0 V 3 GLUTATHIONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.