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HTR3A (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:5-HT-3, 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, 5HT3R, ENTREZ:3359, HGNC:5297, HTR3, HTR3A, MIM:182139, NM_000869, NM_001161772, NM_213621, NP_000860, NP_001155244, NP_998786, NR_046363
Id:ENSG00000166736
Entrez:3359
Ensembl:ENSG00000166736
Description:5-hydroxytryptamine receptor 3A
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HTR3A's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HTR3A.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HTR3A.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HTR3A.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HTR3A.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE205729,GSE205731 2 V 3 TAZEMETOSTAT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE168401 2 V 0 HARMINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE239844 6 V 5 CRIZOTINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE100148 EZH2 inhibition 10 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE239844 11 V 9 CRIZOTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE57871 GLI1 PSMD13 knockdown HCT 116 Vorinostat 8 v 12 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE57871 vorinostat HCT 116 8 v 12 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE176366 vincristine 3 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE128076 doxycycline HEK293 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE205729,GSE205731 2 V 3 TAZEMETOSTAT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE168401 2 V 0 HARMINE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE239844 6 V 5 CRIZOTINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE100148 EZH2 inhibition 10 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE239844 11 V 9 CRIZOTINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE57871 GLI1 PSMD13 knockdown HCT 116 Vorinostat 8 v 12 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE57871 vorinostat HCT 116 8 v 12 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE176366 vincristine 3 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE128076 doxycycline HEK293 1 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.