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PPBP (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, ENTREZ:5473, HGNC:9240, LA-PF4, LDGF, MDGF, MIM:121010, NAP-2, NM_002704, NP_002695, PBP, PPBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
Omim:OMIM:121010
Id:4daf6824-4259-5887-b3c1-aa633c8b9e25
Hgnc:HGNC:9240
Entrez:5473
Ensembl:ENSG00000163736
Description:pro-platelet basic protein
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PPBP's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PPBP.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PPBP.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PPBP.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PPBP.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE82032 trametinib HCC1143 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193541 nifurtimox A-549 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

T62-Spleen Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

GSE193258,GSE193259 2 V 4 OSIMERTINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE82032 3 V 1 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193541 1 V 2 NIFURTIMOX HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE212330 1 V 0 AZACITIDINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193993 SSTR2 knockout 0 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE182150 KIT LSD1 MYC inhibition 4 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE239844 crizotinib 7 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE82032 trametinib HCC1143 3 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193541 nifurtimox A-549 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    T62-Spleen Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    GSE193258,GSE193259 2 V 4 OSIMERTINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE82032 3 V 1 TRAMETINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193541 1 V 2 NIFURTIMOX HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE212330 1 V 0 AZACITIDINE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 0 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE182150 KIT LSD1 MYC inhibition 4 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE239844 crizotinib 7 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.