Synonyms:CLIP4, ENTREZ:53347, HGNC:12462, MIM:605736, NM_001001895, NM_001243467, NM_018961, NP_001001895, NP_001230396, NP_061834, STS-2, TULA, TULA-1, UBASH3A, XM_006724013, XM_011529605, XM_011529606, XM_011529607, XM_011529609, XM_011529610, XP_006724076, XP_011527907, XP_011527908, XP_011527909, XP_011527911, XP_011527912, XR_244316, ubiquitin associated and SH3 domain containing A
Omim:OMIM:605736
Id:ff5222c5-2a55-569b-9fbf-4f3ddf8b2255
Hgnc:HGNC:12462
Description:ubiquitin associated and SH3 domain containing A
This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]