LCE2B (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:26239, HGNC:16610, LCE2B, LEP10, MIM:612610, NM_014357, NP_055172, SPRL1B, XP5, late cornified envelope 2B

Id:ENSG00000159455

Entrez:26239

Ensembl:ENSG00000159455

Description:late cornified envelope 2B

This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LCE2B's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LCE2B.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LCE2B.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LCE2B.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LCE2B.

Results found

Linked to

	Label	Description
	GSE145650 COX2 inhibition 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE174745 dopamine neuron 1 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 trehalose fibroblast 0 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 0 V 2 TREHALOSE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	CLCA2 IDG ionchannel ARCHS4 coexpression Gene Set (Entity type)	A Gene Set from IDG
	ADGRF4 IDG GPCR ARCHS4 coexpression Gene Set (Entity type)	A Gene Set from IDG
	KCNK7 IDG ionchannel ARCHS4 coexpression Gene Set (Entity type)	A Gene Set from IDG
	PIK3C2G IDG kinase ARCHS4 coexpression Gene Set (Entity type)	A Gene Set from IDG
	Beclometasone Down Gene Set (Entity type)	A Gene Set from LINCS
	CDKN2C Down Gene Set (Entity type)	A Gene Set from LINCS

GSE145650 COX2 inhibition 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE174745 dopamine neuron 1 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 trehalose fibroblast 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 0 V 2 TREHALOSE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

CLCA2 IDG ionchannel ARCHS4 coexpression

Gene Set (Entity type)

A Gene Set from IDG

ADGRF4 IDG GPCR ARCHS4 coexpression

Gene Set (Entity type)

A Gene Set from IDG

KCNK7 IDG ionchannel ARCHS4 coexpression

Gene Set (Entity type)

A Gene Set from IDG

PIK3C2G IDG kinase ARCHS4 coexpression

Gene Set (Entity type)

A Gene Set from IDG

Beclometasone Down

Gene Set (Entity type)

A Gene Set from LINCS

CDKN2C Down

Gene Set (Entity type)

A Gene Set from LINCS

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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