RABGEF1 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:27342, HGNC:17676, MIM:609700, NM_001287060, NM_001287061, NM_001287062, NM_001367722, NM_001367723, NM_001367724, NM_001367725, NM_001367726, NM_001367727, NM_001367728, NM_001367729, NM_001367730, NM_001367731, NM_001367732, NM_001367733, NM_001367734, NM_001367735, NM_001367736, NM_001367737, NM_001367738, NM_001367739, NM_001367740, NM_001367741, NM_001367742, NM_001367743, NM_001367744, NM_001367745, NM_001367746, NM_001367747, NM_001367748, NM_001367749, NM_001367750, NM_001367751, NM_001367752, NM_001367753, NM_001367754, NM_001367755, NM_001367756, NM_014504, NP_001273989, NP_001273990, NP_001273991, NP_001354651, NP_001354652, NP_001354653, NP_001354654, NP_001354655, NP_001354656, NP_001354657, NP_001354658, NP_001354659, NP_001354660, NP_001354661, NP_001354662, NP_001354663, NP_001354664, NP_001354665, NP_001354666, NP_001354667, NP_001354668, NP_001354669, NP_001354670, NP_001354671, NP_001354672, NP_001354673, NP_001354674, NP_001354675, NP_001354676, NP_001354677, NP_001354678, NP_001354679, NP_001354680, NP_001354681, NP_001354682, NP_001354683, NP_001354684, NP_001354685, NP_055319, NR_104676, NR_160287, RAB guanine nucleotide exchange factor 1, RABEX5, RABGEF1, RAP1, rabex-5

Omim:OMIM:609700

Id:ENSG00000154710

Hgnc:HGNC:17676

Entrez:27342

Ensembl:ENSG00000154710

Description:RAB guanine nucleotide exchange factor 1

RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RABGEF1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with RABGEF1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RABGEF1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RABGEF1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RABGEF1.

Results found

Linked to

	Label	Description
	GSE242555 1 V 0 NICOTINAMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE228727 2 V 1 DAPAGLIFLOZIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE114492 GSE153671 KMT2D inhibition 6 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE226285 3 V 0 GLUTATHIONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE120370 0 V 6 THROMBIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE148200 0 V 2 GEMCITABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE48812 11 V 6 SULFORAPHANE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE226249 5 V 4 PIRFENIDONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE111247 temozolomide LN-308 0 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE146982 metformin 4 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS