PAM (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:5066, HGNC:8596, MIM:170270, NM_000919, NM_001177306, NM_001319943, NM_001364582, NM_001364583, NM_001364584, NM_001364585, NM_001364586, NM_001364587, NM_001364588, NM_001364589, NM_001364590, NM_001364591, NM_001364592, NM_001364593, NM_001364594, NM_138766, NM_138821, NM_138822, NP_000910, NP_001170777, NP_001306872, NP_001351511, NP_001351512, NP_001351513, NP_001351514, NP_001351515, NP_001351516, NP_001351517, NP_001351518, NP_001351519, NP_001351520, NP_001351521, NP_001351522, NP_001351523, NP_620121, NP_620176, NP_620177, NR_033440, NR_157231, PAL, PAM, PHM, XM_011543419, XM_017009495, XM_017009496, XM_017009497, XM_017009502, XM_017009504, XM_017009505, XM_017009507, XM_017009511, XM_024446066, XM_024446069, XM_024446070, XM_024446072, XM_024446074, XM_024446075, XM_024446076, XM_024446078, XM_024446080, XM_024446081, XM_024446084, XM_024446085, XP_011541721, XP_016864984, XP_016864985, XP_016864986, XP_016864991, XP_016864993, XP_016864994, XP_016864996, XP_016865000, XP_024301834, XP_024301837, XP_024301838, XP_024301840, XP_024301842, XP_024301843, XP_024301844, XP_024301846, XP_024301848, XP_024301849, XP_024301852, XP_024301853, XR_001742084, XR_001742086, XR_002956157, XR_002956158, peptidylglycine alpha-amidating monooxygenase

Omim:OMIM:170270

Id:ENSG00000145730

Hgnc:HGNC:8596

Entrez:5066

Ensembl:ENSG00000145730

Description:peptidylglycine alpha-amidating monooxygenase

This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PAM's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PAM.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PAM.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PAM.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PAM.

Results found

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