WDPCP (Gene)

Organism:

Homo sapiens

Synonyms:BBS15, C2orf86, CHDTHP, CPLANE5, ENTREZ:51057, FRITZ, FRTZ, HGNC:28027, MIM:613580, NM_001042692, NM_001354044, NM_001354045, NM_015910, NP_001036157, NP_001340973, NP_001340974, NP_056994, NR_122106, NR_148704, NR_148705, WD repeat containing planar cell polarity effector, WDPCP, XM_005264348, XM_011532881, XM_011532884, XM_011532887, XM_011532890, XM_011532891, XM_017004253, XM_017004254, XP_005264405, XP_011531183, XP_011531186, XP_011531189, XP_011531192, XP_011531193, XP_016859742, XP_016859743, XR_001738759, XR_001738760, XR_002959303, XR_244934

Omim:OMIM:613580

Id:ENSG00000143951

Hgnc:HGNC:28027

Entrez:51057

Ensembl:ENSG00000143951

Description:WD repeat containing planar cell polarity effector

This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View WDPCP's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with WDPCP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using WDPCP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for WDPCP.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with WDPCP.

Results found

Linked to

	Label	Description
	GSE145990 1 V 0 IBRUTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE217115 3 V 5 ALECTINIB MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE158431 2 V 0 PIOGLITAZONE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE228106 0 V 4 PACLITAXEL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE150055 melphalan cardiac muscle cell 0 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE154074 5 V 0 BLEOMYCIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE208096 1 V 0 PROGESTERONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE157960 0 V 3 PROGESTERONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE152699 GSE152723 vemurafenib 3 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 7 V 13 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE145990 1 V 0 IBRUTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE217115 3 V 5 ALECTINIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE158431 2 V 0 PIOGLITAZONE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE228106 0 V 4 PACLITAXEL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE150055 melphalan cardiac muscle cell 0 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE154074 5 V 0 BLEOMYCIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE208096 1 V 0 PROGESTERONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE157960 0 V 3 PROGESTERONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE152699 GSE152723 vemurafenib 3 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 7 V 13 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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