ATP6V1C2 (Gene)

Synonyms:ATP6C2, ATP6V1C2, ATPase H+ transporting V1 subunit C2, ENTREZ:245973, HGNC:18264, MIM:618070, NM_001039362, NM_144583, NP_001034451, NP_653184, VMA5, XM_011510339, XM_011510340, XM_011510341, XM_017003745, XP_011508641, XP_011508642, XP_011508643, XP_016859234, XR_002959251, XR_922657, XR_922658, XR_922661, XR_922662, XR_922663, XR_922664
Omim:OMIM:618070
Id:ENSG00000143882
Hgnc:HGNC:18264
Entrez:245973
Description:ATPase H+ transporting V1 subunit C2
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]

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