Synonyms:ENTREZ:8631, HEL-S-81p, HGNC:15605, MIM:604969, NM_001075099, NM_003726, NP_001068567, NP_003717, SCAP1, SKAP1, SKAP55, XM_005257755, XM_017025257, XM_017025258, XM_017025259, XM_017025260, XM_024451012, XP_005257812, XP_016880746, XP_016880747, XP_016880748, XP_016880749, XP_024306780, src kinase associated phosphoprotein 1
Omim:OMIM:604969
Nci:C124237
Id:ENSG00000141293
Hgnc:HGNC:15605
Description:src kinase associated phosphoprotein 1
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]