Synonyms:ENTREZ:7743, HGNC:12980, MIM:603132, NM_001278231, NM_001278232, NM_001278240, NM_003452, NM_197977, NP_001265160, NP_001265161, NP_001265169, NP_003443, NP_932094, NR_103480, XM_006717280, XM_006717281, XM_011518998, XM_011518999, XM_017015121, XP_006717343, XP_006717344, XP_011517300, XP_011517301, XP_016870610, ZNF189, zinc finger protein 189
Id:ENSG00000136870
Description:zinc finger protein 189
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]