CFDE Workbench
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CFDE Workbench

TBR1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:10716, HGNC:11590, IDDAS, MIM:604616, NM_006593, NP_006584, T-box brain transcription factor 1, TBR-1, TBR1, TES-56
Omim:OMIM:604616
Id:ENSG00000136535
Hgnc:HGNC:11590
Entrez:10716
Ensembl:ENSG00000136535
Description:T-box brain transcription factor 1
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TBR1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TBR1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TBR1.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TBR1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TBR1.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE173201 0 V 1 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE225375 CDK12 CDK13 inhibition 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE155162 GSE155169 buparlisib 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE185519 3 V 5 GILTERITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE155162,GSE155169 1 V 3 BUPARLISIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115542 digoxin 5 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE173201 cisplatin 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE113369 p53 inhibition 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

Preweaning Lethality, Incomplete Penetrance (MP:0011110)

Gene Set (Entity type)

A Gene Set from KOMP2

  • Gene Set

    GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE173201 0 V 1 CISPLATIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE225375 CDK12 CDK13 inhibition 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE155162 GSE155169 buparlisib 1 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE185519 3 V 5 GILTERITINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE155162,GSE155169 1 V 3 BUPARLISIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115542 digoxin 5 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE173201 cisplatin 2 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE113369 p53 inhibition 2 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    Preweaning Lethality, Incomplete Penetrance (MP:0011110)

    Gene Set (Entity type)

    A Gene Set from KOMP2

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.