APCS (Gene)

Organism:

Homo sapiens

Synonyms:APCS, ENTREZ:325, HEL-S-92n, HGNC:584, MIM:104770, NM_001639, NP_001630, PTX2, SAP, amyloid P component, serum

Id:ENSG00000132703

Entrez:325

Ensembl:ENSG00000132703

Description:amyloid P component, serum

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View APCS's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with APCS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using APCS.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for APCS.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with APCS.

Results found

Linked to

	Label	Description
	GSE168596 2 V 3 ADIPONECTIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE158458 2 V 1 SORAFENIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE228106 3 V 2 PACLITAXEL HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE129389 0 V 3 TROPIFEXOR MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE165174,GSE165175 0 V 1 TRAMETINIB MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE220520 3 V 4 ETHANOL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE220520 1 V 7 ETHANOL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE220520 3 V 9 ETHANOL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE255432 4 V 3 IMEGLIMIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS

GSE168596 2 V 3 ADIPONECTIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE158458 2 V 1 SORAFENIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE228106 3 V 2 PACLITAXEL HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE129389 0 V 3 TROPIFEXOR MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE165174,GSE165175 0 V 1 TRAMETINIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE220520 3 V 4 ETHANOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE220520 1 V 7 ETHANOL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE220520 3 V 9 ETHANOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE255432 4 V 3 IMEGLIMIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.