Synonyms:AGO3, EIF2C3, ENTREZ:192669, HGNC:18421, MIM:607355, NM_024852, NM_177422, NP_079128, NP_803171, XM_005270575, XM_005270576, XM_011540879, XM_011540882, XM_017000523, XM_017000524, XM_017000525, XM_017000526, XM_017000527, XM_017000528, XP_005270632, XP_005270633, XP_011539181, XP_011539184, XP_016856012, XP_016856013, XP_016856014, XP_016856015, XP_016856016, XP_016856017, argonaute RISC catalytic component 3
Omim:OMIM:607355
Id:ENSG00000126070
Hgnc:HGNC:18421
Description:argonaute RISC catalytic component 3
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]