EPX (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:8288, EPO, EPP, EPX, EPX-PEN, EPXD, HGNC:3423, MIM:131399, NM_000502, NP_000493, eosinophil peroxidase

Omim:OMIM:131399

Id:ENSG00000121053

Hgnc:HGNC:3423

Entrez:8288

Ensembl:ENSG00000121053

Description:eosinophil peroxidase

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EPX's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EPX.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EPX.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EPX.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EPX.

Results found

Linked to

	Label	Description
	GSE216043 7 V 9 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE240439 decitabine 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE130437 0 V 1 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE198982,GSE198986 1 V 2 DAUNORUBICIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE168797 2 V 0 CANNABIDIOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE185519 3 V 5 GILTERITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE240439 1 V 2 DECITABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE131649 4 V 8 HEMIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE173116 GSE173118 ML-7 3 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE235066 4 V 0 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE216043 7 V 9 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE240439 decitabine 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE130437 0 V 1 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE198982,GSE198986 1 V 2 DAUNORUBICIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE168797 2 V 0 CANNABIDIOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE185519 3 V 5 GILTERITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE240439 1 V 2 DECITABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE131649 4 V 8 HEMIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE173116 GSE173118 ML-7 3 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE235066 4 V 0 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.